Resumo Introdução: As pessoas que sofrem um Evento Vascular Cerebral (EVC), geralmente, ficam incapacitadas para a realização de suas atividades básicas, isto, envolve uma dependência, por isso é importante a elaboração de um plano de egresso com vasta informação sobre os cuidados, que facilite no profissional de enfermagem proporcionar educação para a saúde, dirigida a familiares e doentes sobre o cuidado no lar trás um EVC. Métodos: O procedimento utilizado para esta proposta consistiu três fases, nas quais, se realizou uma revisão da literatura, uma delimitação com base no tema central, para finalmente, elaborar o plano de egresso que aqui se apresenta. Resultados: Na primeira fase se analisaram 39 estudos, 16 de tipo qualitativo, 11 quantitativos, oito Guias de prática clínica, três mistos e duas teses; posteriormente, na segunda fase se estabeleceu a delimitação do tema com base no critério de evidencia científica e dos diagnósticos enfermeiros da NANDA, e finalmente; na terceira fase, prescreveram-se as principais intervenções de cuidado a implementar trás o egresso de pacientes com EVC. Discussão e conclusões: O plano de egresso forma parte do cuidado integral e humanizado, requer ser feito de forma habitual, para facilitar o diálogo sobre as incertezas, dúvidas e angústias presentes, frequentemente, no cuidador primário e o doente trás seu egresso. As guias de cuidado contribuem a estabelecer o plano de egresso para o doente, com o propósito, de diminuir os reingressos hospitalários, prevenir complicações e melhorar sua qualidade de vida, além de poder seguir inovando a prática clínica de enfermagem.

Abstract Introduction: Persons who suffer a stroke generally are not able to carry out their basic activities and thus become dependent. Because of this, designing discharge plans based on wide-scope information facilitating nursing staff provide healthcare education to victims of stroke and their families is of paramount importance. Methods: In the proposal three stages were considered: a literature review; a main topic delimitation; and a discharge plan, herein featured. Results: In the first stage, 39 studies were analyzed: 16 qualitative; 11 quantitative; 8 clinical practice guides; 3 mixed methods; and 2 dissertations. In the second stage, the main theme was established based on the scientific criteria and the NANDA nursing diagnostics. In the third stage, the main cerebrovascular disease care interventions were prescribed. Discussion and conclusions: The integral discharge plan requires being regularly carried out in order to foster dialogues on related uncertainties, doubts, and anxieties. These care guides can contribute to the establishment of discharge plans aimed at reducing hospital readmissions, preventing complications, and improving the quality of life of these patients.

Resumen Introducción: Las personas que sufren un Evento Vascular Cerebral (EVC), generalmente quedan incapacitadas para la realización de sus actividades básicas, lo que conlleva a una dependencia. Por consiguiente, es importante la elaboración de un plan de egreso con amplia información sobre los cuidados que facilite al profesional de enfermería brindar educación para la salud, dirigida a familiares y enfermos sobre el cuidado en el hogar tras un EVC. Métodos: El procedimiento utilizado para esta propuesta constó de tres fases, en las cuales se realizó una revisión de la literatura, una delimitación con base en el tema central, para finalmente, elaborar el plan de egreso que aquí se presenta. Resultados: En la primera fase se analizaron 39 estudios, 16 de tipo cualitativo, 11 cuantitativos, ocho Guías de práctica clínica, tres mixtos y dos tesis; posteriormente, en la segunda fase se estableció la delimitación del tema con base en el criterio de evidencia científica y los diagnósticos enfermeros de la NANDA, y finalmente; en la tercera fase, se prescribieron las principales intervenciones de cuidado a implementar tras el egreso de pacientes con EVC. Discusión y conclusiones: El plan de egreso forma parte del cuidado integral y humanizado, requiere llevarse a cabo de forma habitual para facilitar el diálogo sobre las incertidumbres, dudas y angustias presentes, frecuentemente, en el cuidador primario y enfermo tras su egreso. A su vez, las guías de cuidado contribuyen a establecer el plan de egreso al enfermo, con el propósito de disminuir los reingresos hospitalarios, prevenir complicaciones y mejorar su calidad de vida, además de poder seguir innovando la práctica clínica de enfermería.

Abstract The microhardness is an essential property of tooth enamel; there may be many factors that alter or diminish this quality causing weakness, one of which is dental fluorosis. The aim of this study was to evaluate the surface microhardness of fluorotic enamel compared with healthy enamel. Two hundred forty extracted human molars were classified into four groups: Healthy (H), mild (MI), moderate (MO) and severe (S) fluorosis according to the Dean index. Micro Vickers Hardness Tester was used to analyze all samples. Average, standard deviation and ranges were calculated for quantitative variables, the ANOVA and Tukey test was used to identify differences between groups. The mean values of surface microhardness in HVN were: H, 333.4; MI, 290.3; MO, 266.1; S, 252.0. The differences between mean surface microhardness among healthy group and fluorotic groups were statistically significant (p < 0.05). This in vitro study confirms that surface microhardness decreased according to the severity of fluorosis.

El despistaje de infecciones mediante pruebas de laboratorio permite disminuir el riesgo de morbimortalidad perinatales y maternas. El objetivo del estudio fue identificar la presencia de infecciones de transmisión vertical: toxoplasmosis, VIH, sífilis, Hepatitis B y C, durante el periodo noviembre 2013 a mayo 2014. Estudio descriptivo, muestra conformada por 175 embarazadas entre 14 a 43 años, a las cuales se les descarto Toxoplasmosis, Anticuerpos Reagínicos por VDRL cualitativa, VIH, hepatitis B (Anti-HBsAg, HBsAg, anti-Core); hepatitis C (Anticuerpos totales), a través de ultramicroELISA (UMELISA). Los resultados arrojaron Anticuerpos Anti Toxoplasma gondii positivas en 27,4%, donde el 31,2% de estas embarazadas presentaron títulos de anticuerpos de 1/512. Los Anticuerpos Anti-VIH resultaron positivos en 0,6%. El 99,4% mostraron un VDRL No Reactivo. El 38,9% tuvo un resultado positivo para anticuerpos contra el antígeno de superficie de la hepatitis B, los marcadores HBsAg y Anti-Core resultaron negativos en un 100%; el 1,7% fue positivo para anticuerpos totales contra el virus de la Hepatitis C. Se concluye que el despistaje de enfermedades infecciosas que representan factores de riesgo de transmisión vertical en embarazadas, constituye uno de los medios más oportuno para diagnosticar estas patologías y prevenir la morbimortalidad materna e infantil.

The screening for infection diseases in pregnancy by laboratory tests can reduce the risk of perinatal and maternal morbidity and mortality. The objective of this study was to identify the presence of vertically transmitted infections: toxoplasmosis, HIV, syphilis, hepatitis B and C, for the period November 2013 to May 2014. Descriptive study, the sample consisted of 175 pregnant women between 14 to 43 years, women who were discarded for Toxoplasmosis, Reaginic Antibodies by qualitative VDRL, HIV, hepatitis B (Anti-HBsAg Anti-HBsAg, anti-Core); hepatitis C (Total antibodies), through ultramicroELISA (UMELISA). The results showed 27.4% positive for Anti- Toxoplasma gondii antibodies, with 31.2% of these pregnant women having antibody titers of 1/512. Anti-HIV antibodies were positive by 0.6%. 99.4% showed Nonreactive VDRL. 38.9% were positive for antibodies against the hepatitis B surface antigen, the markers HBsAg and anti-Core were negative by 100%; 1.7% were positive for total antibodies against Hepatitis C. It is concluded that the screening of infectious diseases that represent risk factors for vertically transmission infections during pregnancy, is one of the most appropriate tools to diagnose these diseases and prevent maternal and infant morbidity and mortality.

The Sierra Grande area, in the province of Río Negro, Argentine, has been particularly affected by trichinellosis, wich remains locally endemic. In the year 2000 a descriptive study was designed to recognize the natural history of trichinellosis in the area and over the period 2001 - 2010 a control program was carried out with early detection of infected pigs using serology by Enzyme-Linked Immunosorbent Assay (ELISA) screening confirmed by Western blot and slaughter and destruction infected pigs. The aim of this study is evaluate the results of control program implemented to reduce the prevalence of trichinellosis in pigs in this area. First results (2001/02) showed that out of 179 pigs studied, 36 (20.1%) were positive. In 2007/08 a total of 277 pigs from 17 breeding farms were studied and only 4 (1.4%) were positive. In 2009/10 all the pigs were negative. No human cases were found during the working period. The control program based on the slaughter of pigs that were serologically positive was successful to limit the prevalence of the disease.

La zona de Sierra Grande, en la provincia de Río Negro, Argentina, se ha visto particularmente afectada por la trichinellosis, la cual sigue siendo endémica a nivel local. En el año 2000 fue diseñado un estudio descriptivo para conocer la historia natural de la trichinellosis en la zona. Durante el período 2001-2010 se llevó a cabo un programa de control en cerdos basado en la detección temprana de anticuerpos específicos mediante enzimoinmunoensayo (ELISA) con confirmación mediante Western blot y el sacrificio de los cerdos positivos. Así, el objetivo del presente trabajo fue evaluar los resultados del programa de control implementado en la reducción de la prevalencia de trichinellosis en cerdos en la localidad de Sierra Grande. Los primeros resultados (2001/02) mostraron que de 179 cerdos estudiados, 36 (20,1%) fueron positivas al sistema diagnóstico (ELISA/WB). En 2007/08 un total de 277 cerdos de 17 criaderos de cerdos fueron estudiados y sólo 4 (1,4%) fueron positivos. En 2009/10 todos los cerdos fueron negativos. No se produjeron casos humanos durante el período de trabajo. El programa de control basado en el sacrificio de cerdos que presentaron anticuerpos específicos anti - Trichinella sp. resultó exitoso en limitar la prevalencia de la enfermedad.

Se registra por primera vez para Colombia la familia Oncopoduridae (Entomobryomorpha: Arthropleona) representada por la especie Harlomillsia oculata. Los ejemplares se recolectaron en cultivo de mora y pastizal de kikuyo circunscritos a bosque alto andino de la cordillera oriental a 2600 msnm de altitud.

The family Oncopoduridae (Entomobryomorpha: Arthropleona), represented by the species Harlomillsia oculata, is reported for the first time in Colombia. The samples were collected in blackberry crops and kikuyu grass pastures belonging to the Andean high forest of the eastern cordillera at 2600 m elevation.

Recently, phonon propagation through atomic structures has become a relevant study issue. The most important applications arise in the thermal field, since phonons can carry thermal and acoustic energy. It is expected that technological advances will make possible the engineering of thermal paths according to convenience. A simple phonon multiplexer was analyzed as a spring-mass model. It consists of mono-atomic chains of atoms with a coupling structure between them. Forces between atoms follow Hooke's law and are restricted to be first nearest neighbor interaction. It was possible to establish simple rules on constitutive parameters such as atom masses and bonding forces that enable one to select a wavelength of transmission. The method used enables the study of structures of much greater complexity than the one presented here.

The purpose of this research was to evaluate the effect of the methan sodium (0,125 l/m²) and biofumigation (chicken manure, 8 kg/m²; wheat bran 1,5 kg/m² and pine needle 30 dm³/m²) as alternative methods for methyl bromide on weed control and chemical characteristics of the soil in carnation crops. The type and number of the weeds and chemical soil characteristics were evaluated before the treatment and 30 days after the carnation crop was implanted. The results show that all the treatments were efficient for the control of weeds in number and species. Only biofumigation with chicken manure and wheat bran were effective to induce changes on the organic matter content and the electric conductivity of the soil. In addition, chicken manure improved the water retention capacity and the nutrients of the soil.

El bromuro de metilo (BM) como desinfectante de suelo está ampliamente generalizado; sin embargo, el planteo de alternativas que lo reemplacen es de vital importancia, dada las restricciones que pesan sobre este producto. Se evaluó el efecto del metam sodio (0,125 L/m²) y la biofumigación (guano de pollo, 8 kg/m²; salvado de trigo 1,5 kg/m² y acícula de pino 30 dm³/m²), como alternativas al tratamiento con bromuro de metilo (80 g/m²), sobre el tipo y número de malezas y las características químicas del suelo en un cultivo de clavel. El tipo y número de malezas presentes y las características químicas del suelo, se evaluaron antes de los tratamientos y a los 30 días después de implantado el cultivo. Los resultados mostraron que todos los tratamientos fueron eficientes para controlar las malezas, en número y especies. Las biofumigaciones con guano de pollo y con salvado de trigo modificaron el contenido de materia orgánica y la conductividad eléctrica del suelo. El guano de pollo adicionalmente aumentó la capacidad de retención de agua y el contenido de nutrientes del suelo.

Insulinoma is a very uncommon tumor in children, with an incidence in adults of 2 per million inhabitants. Clinical manifestations include neuroglycopenic or autonomic manifestations due to hypoglycemia. We describe 2 pediatric patients with insulinoma, characterized by repeated episodes of hypoglycemia associated to high insulin serum levels and presence of a small mass in the pancreas by imaging studies. The diagnosis was very prompt in one case and delayed in the other, emphasizing the need for an appropriate diagnosis of hypoglycemia during childhood

El insulinoma es un tumor muy infrecuente en la edad pediátrica y la incidencia reportada en adultos es de 2 casos por millón de habitantes. La presentación de la enfermedad consiste en la presencia de síntomas neuroglicopénicos y autonómicos desencadenados por los episodios de hipoglicemia. Se describen dos pacientes con insulinoma esporádico. El cuadro clínico consistió en episodios repetidos de hipoglicemia asociados a niveles aumentados de insulina sérica y a imágenes sugerentes de un tumor pancreático. El diagnóstico fue muy oportuno en uno de los casos y muy tardío en el otro, lo que resalta la necesidad de estar muy alerta ante casos de hipoglicemia durante la niñez

Early harvest and forced flower opening with sucrose addition in the preservative solution effects were evaluated during winter and summer, in Moresco, Mabel, Nov and Golden Odino carnation varieties. The flowers were harvested at five dif ferent stages of development: from tight flower buds to open flowers (state 0 to 4). Immediately, these were hydrated during 24 h using a silver thiosulfate solution (0,1 M) at 2 ºC. Then, the flowers were treated with a preservative solution containing citric acid (500 mg l-1) and hydroxyquinoline citrate (60 mg l-1), with and without sucrose (100 g l-1). Petal color, vase life and flower size were evaluated when the full open flower stage was obtained. The flower size was similar during winter and summer in Moresco, Nov and Golden Odino, but the vase life was significantly reduced in the summer. The sucrose addition allowed improving the flower size and the petal color in all the stages of development evaluated. The best flower quality was obtained by combining sucrose addition with the flowers harvested in the stages 2 and 3 in the winter and 0 and 1 in the summer.

Se evaluó la cosecha temprana y la apertura forzada de pimpollos con sacarosa, en invierno y en verano, en flores de 4 variedades de clavel (Moresco, Mabel, Nov y Golden Odino). Las flores fueron cosechadas en cinco estados de desarrollo, desde botón cerrado hasta flor abierta (estados 0 al 4), hidratadas en frío (2 ºC) con una solución de tiosulfato de plata (0,1 M) durante 24 horas y luego transfe ridas a una solución de ácido cítrico (500 mg l-1) y citrato de hydroxyquinoleina (60 mg l-1); la solución de apertura contenía, además, 100 g l-1 de sacarosa. Cuando se completó la apertura de la flor se evaluó tamaño, intensidad de color y vida en el vaso. El tamaño de la flor fue similar en invierno y verano en las varie dades Moresco, Golden Odino y Nov, sin embargo, en todas las variedades la vida en el vaso fue menor en verano. El agregado de sacarosa mejoró la aper tura, el tamaño de las flores e intensificó los colores en todas las variedades y estados de corte. La mayor calidad se logró combinando el agregado de saca rosa y la cosecha en estado 0 -1 en verano y 2 -3 en invierno.

Background: Recently, the cut-off point for normal fasting glucose (FG) level, was decreased to 100 mg/dl. Aim: To determine the frequency of abnormal carbohydrate abnormalities in children with obesity and evaluate if the fasting glucose level is a useful tool for the screening of glucose intolerance (GI). Patients and methods: Children and adolescents, referred for evaluation of obesity were evaluated with an oral glucose tolerance test (OGTT) and FG. The sensitivity of FG for detection of GI, using the 100 and 110 mg/dl cut-off point, was evaluated. Results: We studied 186 patients (125 females) aged 12.1 (range: 5.4-19.3) years with a body mass index (BMI) of 29.9 (18.3-44.6) kg/mt² and a BMI Z score of 2.1 (1.7-3.2). Seven patients (3.8%) had abnormalities in the carbohydrate metabolism. The sensitivity of FG for the detection of GI using the 100 and 110 mg/dl cut-off values was 42.9 and 14.3%, respectively. Receiver operating characteristic (ROC) curves showed that the optimal diagnostic level for FG corresponds to 80 mg/dl (sensitivity: 85.7% and specificity of 74.9%). Conclusions: An abnormal carbohydrate metabolism was detected in 3.8% of the obese children and adolescents in this sample. FG of 100 mg/dl does not detect 57.1% of the patients with glucose intolerance. These data suggest that FG is not a useful screening tool for glucose intolerance in young patients

Background: The lack of catch up growth (CUG) in small for gestational age (SGA) children may be related to a reduced sensitivity to insulin growth factor 1 (IGF-I). Aim: To assess the sensitivity to IGF-I in small for gestational age children, measuring basal and post IGF-I nocturnal profile of growth hormone (GH). Patients and methods: We studied 34 prepubertal SGA children aged 4 to 11 years. Twenty three had CUG and 11 did not have CUG. As an IGF-I sensitivity test, nocturnal GH levels were measured every 20 minutes from 23:00 h to 07:00 h, both under baseline conditions and after the administration of a subcutaneous bolus of 1 mg/kg/body weight of the IGF-I + IGFBP-3 complex (Somatokine®). Results: At the time of the study, the Z scores for height among children with and without CUG were -1.55 ± 0.22 and -3.24 ± 0.28, respectively (p <0.0001). There were no statistical differences between CUG + vs CUG- patients in mean basal GH (6.6 ± 0.5 and 5.6 ± 0.6 ng/ml, respectively). After Somatokine® administration, mean GH, and the mean GH area under the curve (AUC) decreased significantly in both groups. However, mean overnight GH AUC decreased in all SGA children with CUG, after Somatokine® administration, whereas 3 out of 11 SGA children without CUG had an increase in their mean GH AUC in response to Somatokine®. Conclusions: These findings suggest that pituitary sensitivity to IGF-I may be decreased in some SGA children without CUG

Composites made by hand lay-up are directed influenced by some fabrication factors, e.g. the stacking sequence, fiber volume fraction, as well as the cure process This study takes into consideration an E-glass/epoxy plain weave woven fabric composite made by hand lay-up. After the stacking sequence is completed, three sets of plates are selected and each one is cured differently. The three selected cure processes are: cure on air, cure vacuum assisted, and cure under compression. A variance study based on stiffness from ASTM D 3039/3039M tensile tests is performed to check the statistical differences caused by the cure processes. Additionally, a microscopic analysis is performed to identify the voids formation rate. The coupling between macro and micro-mechanical analysis is done by a non-dimensional coefficient which is able to capture the rate of defects generated by each cure process.

Introduction: During the last decade the importance of glycaemic control in the prevention of microvascular complications of type 1 diabetes mellitus (DM1) has been demostrated. To achieve this goal, different modalities of intensive therapy have been recommended. Objective: To communicate a novel therapeutic modality employed in paedriatric patients and the metabolic control achieved. Methods: All DM patients < 19 years were included. Insulin treatment was consigned and classified as intensive (at least 3 daily doses, 2 or 3 NPH daily doses, or glargin) or conventional (2 or less doses). Number of doses, mean HbA1c during 2003, results of educative programmes were evaluated and compared. Results: 69 patients (36 females) were studied, 59,7% were pubertal, with a mean age of 12,0 ± 3,7 years. All patients used a basal insulin (69,2% daily dose) and a prandial insulin. Intensive therapy was used by 87% of children. Patients with multiple daily doses received 3 or 4 inyections of a short or rapid acting insulin. Basal insulin was glargine in 10%, twice daily NPH in 28% and thrice daily in 49%. Patients modified dose according to glucose level occured in 88,4%, and 46,4% considered carbohydrate intake. 27% knew the carbohydrate/insulin ratio and 79,7% used additional insulin when eating extra carbohydrates. The BbA1c was 8,6 ± 1,4% without differences in terms of insulin modality used. 30,4% achieved the proposed goals of HbA1c. The total and basal insulin usage correlated with the HbA1c. Conclusions: Multiple modalities of insulin therapy are available, no difference in metabolic control between the modalities was detected. We have achieved very good control in 30% of the patients, only insulin daily dose and basal dose correlated significatively with HbA1c

En la última década se ha demostrado la importancia del control glicémico en la prevención de las complicaciones microvasculares de la DM1. Para lograr este objetivo se ha propiciado el uso de esquemas terapéuticos de insulina intensificados. Objetivo: Comunicar los nuevos esquemas terapéuticos que se utilizan en niños y adolescentes con DM1 y sus resultados en el control metabólico. Método: Se evaluaron los esquemas insulínicos utilizados por todos los pacientes < 19 años en control durante 2003, clasificándolos en tratamiento intensificado (doble o triple dosis de NPH o Glargina) o convencional (< 2 dosis/día). Se consignaron las dosis utilizadas, la HbA1c promedio, el resultado del programa educativo (conocimiento de cantidad de hidratos de carbono, intercambio de alimentos, cambio de dosis según ingesta de hidratos de carbono (HdC) y proporción Insulina/ HdC) y se compararon los resultados obtenidos con las distintas modalidades de tratamiento. Resultados: Se estudiaron 69 pacientes con DM1 (36 mujeres), de 12,0 ± 3,7 años (2-19 años), 59,7% púberes. Todos utilizaban una insulina basal (69,2% de la dosis diaria) y otra prandial; 87% de los pacientes requirieron tres o más dosis diarias de insulina y 13% utilizaba esquema convencional de dos dosis de NPH. Los pacientes en tratamiento intensificado recibían tres o cuatro dosis diarias de insulina prandial, con los siguientes esquemas de insulina basal: dos dosis diarias de NPH (28%), glargina (10%) y tres dosis diarias de NPH (49%). 88,4% de los pacientes modificaba la dosis de insulina rápida según la glicemia y 46,4% consideraba la ingesta de HC; 27% conocía la relación HdC/insulina y 79,7% se colocaba refuerzos adicionales de insulina al comer fuera de sus horarios. La HbA1C del grupo fue de 8,6 ± 1,4%; 30,4% de los pacientes logró el objetivo de HbA1c establecido en el programa, sin diferencias respecto al esquema de insulinoterapia basal utilizado. Por análisis de covarianza sólo la dosis total y basal de insulina se correlacionaron significativamente con la HbA1C (p < 0,05). Conclusiones: Utilizamos una amplia variedad de esquemas terapéuticos con insulina y no encontramos diferencias en control metabólico entre los distintos esquemas. 30% de nuestros pacientes logran adecuado control metabólico. Sólo la dosis total y basal de insulina se correlacionan con los valores de HbA1c

Background: Recent studies in the United States have demonstrated that a significant proportion of girls show thelarche before the age of eight years. Nutritional status, geographic influences and racial factors are known to affect the timing of puberty. Aim: To evaluate the age of onset of puberty, development of secondary sexual characteristics and menarche in Chilean girls, and its relation to obesity and socioeconomic status. Material and methods: Healthy girls attending elementary school, from first to ninth grade in Santiago, Chile, were studied. A pediatric endocrinologist evaluated pubertal development using Tanner classification. Breast development was assessed by inspection and breast palpation. Average age of onset of pubertal events was determined by probit analysis. Results: A total of 758 girls, aged 5.8 to 16.1 years, were recruited. Obesity, defined as a BMI greater than 90th percentile, was found in 24.4%. The age of menarche was 12.7 years, the onset of Tanner stage 2 breast development and pubic hair was at 8.9 and 10.4 years, respectively. Sixteen percent of girls aged 7 to 7,9 years, had thelarche. Upper class girls showed a later onset of breast Tanner stage 4 stage than low-middle class girls. Obesity was not found in logistic regression analysis to be a significant predictive factor in the onset of puberty. Conclusions: The age of menarche has not changed in the last thirty years, but an earlier onset of thelarche has occurred. The high frequency of thelarche between 7 and 8 years suggests that the normal age of breast development should be revised (Rev Méd Chile 2004; 132: 801-8)

During the last decade, the importance of glycemic control in the prevention of the microvascular complications of type 1 Diabetes Mellitus (DM1) was clearly demonstrated. Aim: To evaluate the metabolic and anthropometric results of a multidisciplinary intensified treatment program of DMI in children and adolescents. Patients and methods: Report of 54 patients treated during 2001. The intensified treatment consisted of: multiple daily doses of insulin, frequent glycemic control, nutritional, psychological and educational support, and permanent availability of a diabetes nurse for telephonic support. Results: Thirty one patients were female, their mean age was 10.4±0.5 years old and 52% were experiencing puberty. Fifty three percent of the patients used 3 insulin doses per day, 95% changed rapid insulin dose based on glucose levels and 18% considered carbohydrates in their rapid insulin dosing. Mean glycosilated hemoglobin was 8.18±0.23% without differences by sex or pubertal status. Sex, pubertal stage and the number of insulin doses did not contribute to glycosilated hemoglobin changes. There were no differences in weight or BMI, but there was a decrease in height Z score from the admission to the program until the last control (0.1±0.1 vs -0.3±0.1 DS; p <0.01). Conclusions: A modified intensified modality of DM1 therapy for pediatric patients in a public hospital in Chile is feasible, achieving similar metabolic control, compared to international large centers (Rev Méd Chile 2003; 131: 857-64)